该基因编码的蛋白质是atp结合盒（abc）转运蛋白超家族的成员。abc蛋白通过细胞外和细胞内的膜运输各种分子。ABC基因分为七个不同的亚家族（ABC1，MDR/TAP，MRP，ALD，OABP，GCN20，White）ABC全转运蛋白是MRP亚家族的一员，参与多药耐药该基因的产物参与胆汁酸、结合类固醇和环核苷酸的生理过程。此外，该基因中的一个单核苷酸多态性（snp）负责确定人类耳垢的类型。这个基因和家族成员ABCC12被确定是通过复制获得的，并且都定位在染色体16q12.1上已经描述了该基因的多个选择性剪接转录变体。[由RefSeq提供，2008年7月]
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]