该基因编码的蛋白是血管生成素1(angiopoietin 1,ANGPT1)和内皮细胞TEK酪氨酸激酶(TIE-2,TEK)的拮抗剂编码蛋白破坏血管重塑能力,可能诱导内皮细胞凋亡。已经发现了三个编码三种不同亚型的转录变体[由RefSeq提供,2008年7月]
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

基因名:ANGPT2
别名:ANG2,AGPT2
基因ID:285
Chromosome:
(GRCh37)
8 Start: 6357172 End: 6420784 Strand: 
信号通路:  
ANGPT2 基因突变与药物

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