该基因编码一种磷酸肌醇结合蛋白,包含ARF-GAP、RHO-GAP、RAS结合和pleckstrin同源结构域ARF-GAP和RHO-GAP结构域协同介导细胞骨架和细胞形态的重排是一种特异性的PtdIns(3,4,5)P3/PtdIns(3,4)P2刺激的Arf6间隙蛋白已发现该基因的选择性剪接转录本,但其生物学有效性尚未确定[由RefSeq提供,2015年9月]
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Sep 2015]

基因名:ARAP3
别名:DRAG1,CENTD3
基因ID:64411
Chromosome:
(GRCh37)
5 Start: 141032968 End: 141061800 Strand: 
信号通路:  
ARAP3 基因突变与药物

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