由该基因编码的蛋白质是一个含有ankyrin重复序列和SOCS盒(ASB)的蛋白质家族的成员它们包含锚定蛋白重复序列和SOCS盒结构域socs盒用于将细胞因子信号(socs)蛋白的抑制因子及其结合伙伴与elongin b和c复合物结合,可能将其作为降解的靶点。[由RefSeq提供,2017年2月]
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Feb 2017]
基因名: | ASB18 |
别名: | ASB-18 |
基因ID: | 401036 |
Chromosome: (GRCh37) | 2 Start: 237103515 End: 237172988 Strand: |
信号通路: |