P型atp酶，如atpp11b，在其中间状态被磷酸化，并推动离子在膜上的上坡转运已鉴定出P型atp酶的几个亚家族一个亚科运输重金属离子，如cu（2+）、cd（2+）。另一个亚科运输非重金属离子，如H+、Na+、K+、或Ca+。第三个亚科运输两栖动物，如磷脂酰丝氨酸。
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]