该基因编码的蛋白质包含cg1-dna结合域、转录因子免疫球蛋白域、锚蛋白重复序列和钙调素结合iq基序。编码蛋白被认为是一种转录因子,可能是一种肿瘤抑制因子然而,有时在该基因和wwtr1基因之间观察到易位事件,由此产生的wwtr1-camta1癌蛋白导致上皮样血管内皮瘤,一种恶性血管癌。[由RefSeq提供,2017年3月]
The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. [provided by RefSeq, Mar 2017]

基因名:CAMTA1
别名:CANPMR
基因ID:23261
Chromosome:
(GRCh37)
1 Start: 6845384 End: 7829766 Strand: 
信号通路:  
CAMTA1 基因突变与药物

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