该基因编码一种在细胞分裂调控中起关键作用的保守蛋白编码的蛋白引导细胞周期蛋白B结合的CDC2去磷酸化并触发有丝分裂它也抑制p53诱导的生长停滞。已经描述了该基因的多个选择性剪接转录变体。[由RefSeq提供，2015年12月]
This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Dec 2015]