这个基因的产物是检查点激酶1的一个重要上游调节因子,并触发细胞周期的检查点阻滞,以应对复制应激或dna损伤。在正常的s期,这种蛋白质也是有效的dna复制所必需的。已发现该基因编码不同亚型的多个转录变体。[由RefSeq提供,2010年6月]
The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

基因名:CLSPN
别名:
基因ID:63967
Chromosome:
(GRCh37)
1 Start: 36185819 End: 36235568 Strand: 
信号通路:  
CLSPN 基因突变与药物

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