该基因编码一条α链，用于一种低丰度的纤维胶原纤维胶原分子是由一种或多种α链组成的三聚体V型胶原存在于含有I型胶原的组织中，似乎调节由I型胶原和V型胶原组成的异型纤维的组装。该基因产物与XI型胶原密切相关，可能V型和XI型胶原链通过组织特异性链组合构成单一胶原类型该基因突变与埃勒斯-丹洛综合征I型和II型相关。[由RefSeq提供，2008年7月]
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq, Jul 2008]