该基因编码细胞色素P450酶超家族的一个成员细胞色素p450蛋白是一种单加氧酶,催化药物代谢和胆固醇、类固醇等脂类的合成。这种蛋白质定位于内质网,其底物尚未确定。该基因产生两个转录变体,是来自染色体19q上cyp2a、cyp2b和cyp2f亚家族的大量细胞色素p450基因簇的一部分。
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

基因名:CYP2A7
别名:CPA7,CPAD,CYP2A,CYPIIA7,P450-IIA4
基因ID:1549
Chromosome:
(GRCh37)
19 Start: 41381344 End: 41388657 Strand: 
信号通路:  
CYP2A7 基因突变与药物

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