该基因编码的蛋白质在序列上与rna外显体的3'/5'外核溶解亚基相似。外显子是一个大的多聚核苷酸复合物，负责降解各种rna底物。已经发现了一些转录变体，有些是蛋白质编码的，有些不是。[由RefSeq提供，2012年3月]
The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Mar 2012]