该基因编码一种具有5'到3'外切酶活性和RNase H活性的蛋白质它类似于酿酒酵母蛋白外显子1，它与msh2相互作用，参与错配修复和重组。这个基因的选择性剪接导致三个转录变体编码两个不同的亚型[由RefSeq提供，2008年7月]
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]