该基因编码的蛋白是γ免疫球蛋白(igg)fc区的低亲和力受体。编码蛋白作为单体,可以结合单体或聚集的igg。该基因可能在外周循环中捕获免疫复合物已经发现了一些编码不同亚型的转录变体。在1号染色体上也发现了一个编码相关蛋白的高度相似的基因[由RefSeq提供,2012年8月]
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

基因名:FCGR3B
别名:CD16,FCG3,CD16A,CD16b,FCGR3,FCGR3A,FCR-10,FCRIII,FCRIIIb
基因ID:2215
Chromosome:
(GRCh37)
1 Start: 161592986 End: 161601753 Strand: 
信号通路:  
FCGR3B 基因突变与药物

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