该基因编码叶酸受体（FOLR）蛋白家族的一个成员，其对叶酸和几种还原叶酸衍生物具有高度亲和力，并介导5-甲基四氢叶酸向细胞内部的传递该基因在卵巢癌和原发性腹膜癌中的表达可能升高。这个基因存在于11号染色体上的一个基因簇中。选择性剪接导致多个转录变体[由RefSeq提供，2015年12月]
This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]