由该基因编码的分泌蛋白在胃表面粘液细胞中产生,可与三叶因子家族肽1或胃动素1结合。该基因可能是一个抑癌基因,因为它在胃癌组织中的表达明显减少。编码蛋白与胃动素-1相互作用,调节胃粘膜的稳态。[由RefSeq提供,2015年12月]
The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. [provided by RefSeq, Dec 2015]

基因名:GKN2
别名:GDDR,TFIZ1,PRO813,BRICD1B,VLTI465
基因ID:200504
Chromosome:
(GRCh37)
2 Start: 69172364 End: 69180102 Strand: 
信号通路:  
GKN2 基因突变与药物

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