由该基因编码的分泌蛋白在胃表面粘液细胞中产生，可与三叶因子家族肽1或胃动素1结合。该基因可能是一个抑癌基因，因为它在胃癌组织中的表达明显减少。编码蛋白与胃动素-1相互作用，调节胃粘膜的稳态。[由RefSeq提供，2015年12月]
The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. [provided by RefSeq, Dec 2015]