该基因编码的膜蛋白是一个超极化激活的阳离子通道，参与心脏和神经元的固有起搏电流。编码蛋白可与其他成孔亚单位发生均二聚或异二聚，形成钾通道这个通道可能是酸味的受体[由RefSeq提供，2011年10月]
The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011]