在脊椎动物中,编码一类转录因子的基因被称为同源盒基因,它们在四条独立的染色体上以a、b、c和d的形式存在。这些蛋白的表达在胚胎发育过程中受到时空调控。这个基因是7号染色体上一个簇的一部分,编码一个DNA结合转录因子,它可以调节基因的表达、形态发生和分化。编码蛋白中的多丙氨酸束扩张可引起手足子宫综合征,也称为手足生殖器综合征。[由RefSeq提供,2008年7月]
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. [provided by RefSeq, Jul 2008]

基因名:HOXA13
别名:HOX1,HOX1J
基因ID:3209
Chromosome:
(GRCh37)
7 Start: 27236499 End: 27239725 Strand: 
信号通路:  
HOXA13 基因突变与药物

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