这个基因编码热休克蛋白70家族的一个成员,它包含热诱导和组成性表达的成员。这种蛋白质属于后者,也被称为热休克同源蛋白它作为一种伴侣,与新生的多肽结合以促进正确的折叠。它还作为一种atp酶,在膜组分通过细胞运输过程中分解氯氰菊酯包被的囊泡另外,已经发现该基因编码不同亚型的剪接转录变体[由RefSeq提供,2011年8月]
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

基因名:HSPA8
别名:LAP1,HSC54,HSC70,HSC71,HSP71,HSP73,LAP-1,NIP71,HEL-33,HSPA10,HEL-S-72p
基因ID:3312
Chromosome:
(GRCh37)
11 Start: 122928200 End: 122933074 Strand: 
信号通路:  
HSPA8 基因突变与药物

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