这个基因(ifngr1)编码γ干扰素受体的配体结合链(α)。人干扰素γ受体是ifngr1和ifngr2的异二聚体。ifngr1基因变异与幽门螺杆菌感染易感性有关。此外,ifngr1的缺陷是孟德尔对分枝杆菌病(也称为家族性播散性非典型分枝杆菌感染)易感性的原因。[由RefSeq提供,2008年7月]
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]

基因名:IFNGR1
别名:CD119,IFNGR,IMD27A,IMD27B
基因ID:3459
Chromosome:
(GRCh37)
6 Start: 137518621 End: 137540981 Strand: 
信号通路:  
IFNGR1 基因突变与药物

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