ikbke是一种非特异性的i-kappa-b激酶(见mim 164008),对调节抗病毒信号通路至关重要。ikbke也被确定为乳腺癌(mim 114480)癌基因,在超过30%的乳腺癌和乳腺癌细胞系中被扩增和过度表达(hutti等人,2009年[pubmed 19481526])。[由omim提供,2009年10月]
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009]

基因名:IKBKE
别名:IKKE,IKKI,IKK-E,IKK-i
基因ID:9641
Chromosome:
(GRCh37)
1 Start: 206643586 End: 206670223 Strand: 
信号通路: 免疫相关 
IKBKE 基因突变与药物

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