该基因编码KIT位点编码的酪氨酸激酶受体配体这种配体是一种多效性因子,在子宫生殖细胞、神经细胞发育和造血中起作用,所有这些都被认为反映了细胞迁移的作用在成人中,它的功能是多方面的,而主要是以它在造血方面的持续需求而闻名。已经发现了两个编码不同亚型的转录变体。[由RefSeq提供,2008年7月]
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
基因名: | KITLG |
别名: | SF,MGF,SCF,SLF,DCUA,FPH2,FPHH,KL-1,Kitl,SHEP7,DFNA69 |
基因ID: | 4254 |
Chromosome: (GRCh37) | 12 Start: 88886570 End: 88974250 Strand: |
信号通路: |