该基因编码一个富含亮氨酸的重复激酶和一个GDP/GTP结合蛋白的多结构域蛋白。编码的蛋白质被认为在调节骨量中起作用缺乏相似基因的小鼠表现出严重的骨石化，骨矿化增加，骨吸收减少[由RefSeq提供，2017年1月]
This gene encodes a multi-domain protein that is a leucine-rich repeat kinase and a GDP/GTP binding protein. The encoded protein is thought to play a role in the regulation of bone mass. Mice lacking a similar gene showed severe osteopetrosis, increased bone mineralization and decreased bone resorption. [provided by RefSeq, Jan 2017]