MAD1L1是有丝分裂纺锤体装配检查点的一个组成部分,它可以防止后期的发生,直到所有染色体在中期板上正确排列mad1l1作为同二聚体发挥作用,并与mad2l1相互作用。mad1l1可能在细胞周期调控和肿瘤抑制中发挥作用。选择性剪接导致多个转录变体[由RefSeq提供,2015年1月]
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
基因名: | MAD1L1 |
别名: | MAD1,PIG9,TP53I9,TXBP181 |
基因ID: | 8379 |
Chromosome: (GRCh37) | 7 Start: 1855428 End: 2272583 Strand: |
信号通路: |