该基因编码的蛋白质与阿托品-1相互作用。阿托品-1含有一个多聚谷氨酸重复序列，其扩增导致齿龈和苍白球萎缩。该编码蛋白具有两个ww结构域，一个鸟苷酸激酶样结构域和多个pdz结构域。其结构与膜相关鸟苷酸激酶同源物（maguk）家族相似。[由RefSeq提供，2008年7月]
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]