该基因编码一种与酵母SIN1蛋白（一种应激激活蛋白激酶）高度相似的蛋白质另外，还描述了编码不同亚型的剪接转录变体。已鉴定出该基因转录本的交替多聚腺苷酸化位点和交替3’utr[由RefSeq提供，2008年7月]
This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene. [provided by RefSeq, Jul 2008]