该基因编码一种具有三个HTH-DNA结合域的蛋白质,作为转录调节器。这种蛋白在造血调节中起着重要作用。该基因可能在白血病和淋巴瘤中异常表达、重排或易位,被认为是癌基因。选择性剪接导致多个转录变体。
This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants.

基因名:MYB
别名:Cmyb,c-myb,c-myb_CDS,efg
基因ID:4602
Chromosome:
(GRCh37)
6 Start: 135502453 End: 135540311 Strand: 1
信号通路: 细胞增殖 
MYB 基因突变与药物

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