该基因编码丝氨酸/苏氨酸激酶家族的一个成员,该家族包含两个PAS结构域该基因的表达受葡萄糖调节,编码蛋白在胰岛素基因表达调控中起作用这种基因的下调可能在2型糖尿病中起作用。另外,已经观察到该基因编码多个亚型的剪接转录变体[由RefSeq提供,2011年11月]
This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
基因名: | PASK |
别名: | STK37,PASKIN |
基因ID: | 23178 |
Chromosome: (GRCh37) | 2 Start: 242045514 End: 242089394 Strand: |
信号通路: |