这个基因编码四个哺乳动物对应的果蝇“dunce”基因中的一个。编码蛋白具有3',5'-环腺苷酸磷酸二酯酶活性,降解camp,在多种细胞类型中充当信号转导分子。该基因使用不同的启动子产生多个交替剪接的转录变体,编码功能蛋白。[由RefSeq提供,2009年9月]
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]
基因名: | PDE4D |
别名: | DPDE3,PDE43,STRK1,ACRDYS2,HSPDE4D,PDE4DN2 |
基因ID: | 5144 |
Chromosome: (GRCh37) | 5 Start: 58264865 End: 59783925 Strand: |
信号通路: |