这个基因编码四个哺乳动物对应的果蝇“dunce”基因中的一个。编码蛋白具有3',5'-环腺苷酸磷酸二酯酶活性,降解camp,在多种细胞类型中充当信号转导分子。该基因使用不同的启动子产生多个交替剪接的转录变体,编码功能蛋白。[由RefSeq提供,2009年9月]
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]

基因名:PDE4D
别名:DPDE3,PDE43,STRK1,ACRDYS2,HSPDE4D,PDE4DN2
基因ID:5144
Chromosome:
(GRCh37)
5 Start: 58264865 End: 59783925 Strand: 
信号通路:  
PDE4D 基因突变与药物

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