磷酸肌醇3激酶(pi3ks)是肌醇磷脂的磷酸化产物,参与免疫应答。该基因编码的蛋白质是PI3K的I类催化亚单位,与其他I类催化亚单位(p110αp110β和p110δ)一样,编码蛋白结合p85调节亚单位形成pi3k,该基因位于先前在髓性白血病中发现的第7号染色体的一个普遍缺失片段。已经发现了一些编码相同蛋白质的转录变体。[由RefSeq提供,2015年6月]
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015]

基因名:PIK3CG
别名:PI3K,PIK3,PI3CG,PI3Kgamma,p110gamma,p120-PI3K
基因ID:5294
Chromosome:
(GRCh37)
7 Start: 106505723 End: 106547592 Strand: 
信号通路: 细胞增殖  免疫相关  炎症相关  凋亡抑制  能量代谢 
PIK3CG 基因突变与药物

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