磷脂酰肌醇3激酶(pi3k)磷酸化磷脂酰肌醇和类似的化合物,然后作为第二信使的生长信号途径。pi3k由一个催化亚基和一个调节亚基组成。该基因编码的蛋白代表pi3k的一个调节亚单位,编码的蛋白包含两个sh2结构域,通过这两个结构域结合活化的蛋白酪氨酸激酶来调节其活性。[由RefSeq提供,2016年6月]
Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016]

基因名:PIK3R3
别名:p55,p55PIK,p55-GAMMA
基因ID:8503
Chromosome:
(GRCh37)
1 Start: 46505812 End: 46642167 Strand: 
信号通路:  
PIK3R3 基因突变与药物

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