该基因编码prdi-bf1和riz同源结构域(prdm)家族的一个成员。编码蛋白可能具有组蛋白甲基转移酶活性,并通过抑制分化标记基因的表达在细胞多能性中发挥重要作用这种基因的表达可能在乳腺癌中起作用。[由RefSeq提供,2011年12月]
This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer. [provided by RefSeq, Dec 2011]
基因名: | PRDM14 |
别名: | PFM11 |
基因ID: | 63978 |
Chromosome: (GRCh37) | 8 Start: 70963886 End: 70983562 Strand: |
信号通路: |