该基因编码一种与酿酒酵母突变蛋白rev1相似的蛋白质。Rev1蛋白包含一个BRCT结构域,在蛋白质-蛋白质相互作用中起重要作用人类Rev1样蛋白的一个建议作用是作为一种支架,招募DNA聚合酶参与受损DNA的转运合成(TLS)[由RefSeq提供,2016年3月]
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. [provided by RefSeq, Mar 2016]

基因名:REV1
别名:REV1L,AIBP80
基因ID:51455
Chromosome:
(GRCh37)
2 Start: 100016938 End: 100106480 Strand: 
信号通路:  
REV1 基因突变与药物

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