该基因编码丝氨酸/苏氨酸激酶rsk(核糖体s6激酶)家族的一个成员。该激酶包含2个不同的激酶催化结构域并磷酸化各种底物,包括丝裂原活化激酶(MAPK)信号通路的成员这种蛋白的活性与控制细胞的生长和分化有关。交替转录剪接变体,编码不同的亚型,已经被描述出来。[由RefSeq提供,2008年7月]
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

基因名:RPS6KA1
别名:RSK,HU-1,RSK1,p90Rsk,MAPKAPK1,MAPKAPK1A
基因ID:6195
Chromosome:
(GRCh37)
1 Start: 26856249 End: 26901520 Strand: 
信号通路:  
RPS6KA1 基因突变与药物

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