该基因编码的蛋白质在细胞核中表达,是一种调节细胞分裂过程中姐妹染色单体内聚的内聚蛋白复合物的亚单位。该基因突变与卵巢早衰有关。交替剪接导致编码不同亚型的多个转录变体。这个基因有多个假基因。
The protein encoded by this gene is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes.

基因名:STAG3
别名:
基因ID:10734
Chromosome:
(GRCh37)
7 Start: 99775186 End: 99819111 Strand: 1
信号通路:  
靶向药: 维莫非尼,威罗菲尼 
化疗药:
STAG3 基因突变与药物

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