该基因编码核外激素受体复合物的β亚单位,该复合物与核定位信号相互作用,将核蛋白靶向细胞核。核外激素受体复合物是一个识别核定位信号的α亚单位和一个β亚单位的异二聚体,β亚单位将复合物固定在核孔蛋白上。这个基因的交替剪接导致编码不同蛋白质的几种转录变体[由RefSeq提供,2018年6月]
This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in several transcript variants encoding different proteins. [provided by RefSeq, Jun 2018]

基因名:TNPO1
别名:MIP,TRN,IPO2,MIP1,KPNB2
基因ID:3842
Chromosome:
(GRCh37)
5 Start: 72112418 End: 72210215 Strand: 
信号通路:  
TNPO1 基因突变与药物

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