该基因编码一种与拓扑异构酶iiβ的c末端区域相互作用的结合蛋白。这种相互作用表明,这种蛋白质在拓扑异构酶IIβ通过短暂的DNA链断裂的催化反应中起支持作用[由RefSeq提供,2008年7月]
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]
基因名: | TOPBP1 |
别名: | Dpb11,TOP2BP1 |
基因ID: | 11073 |
Chromosome: (GRCh37) | 3 Start: 133319449 End: 133380762 Strand: |
信号通路: |