该基因编码一种与拓扑异构酶iiβ的c末端区域相互作用的结合蛋白。这种相互作用表明,这种蛋白质在拓扑异构酶IIβ通过短暂的DNA链断裂的催化反应中起支持作用[由RefSeq提供,2008年7月]
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]

基因名:TOPBP1
别名:Dpb11,TOP2BP1
基因ID:11073
Chromosome:
(GRCh37)
3 Start: 133319449 End: 133380762 Strand: 
信号通路:  
TOPBP1 基因突变与药物

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