该基因编码泛素特异性处理(ubp)蛋白酶家族的一个成员,该蛋白酶是一种具有his和cys结构域的二氢泛素化酶(dub)。该蛋白位于细胞质中,从泛素融合前体和泛素化蛋白中分离泛素部分。该蛋白特异性地在Fanconi贫血(FA)DNA修复途径中的一种蛋白质交替转录剪接变体已经被描述[由RefSeq提供,2008年7月]
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

基因名:USP1
别名:UBP
基因ID:7398
Chromosome:
(GRCh37)
1 Start: 62901975 End: 62917475 Strand: 
信号通路:  
USP1 基因突变与药物

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