该基因编码一种属于b7共刺激蛋白家族的蛋白质。这个家族的蛋白质存在于抗原提呈细胞的表面,并与t细胞表面受体结合的配体相互作用。研究表明,高水平的编码蛋白与肿瘤的进展有关。这个基因的一个假基因位于20号染色体上。已发现该基因编码不同亚型的多个转录变体。[由RefSeq提供,2011年12月]
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

基因名:VTCN1
别名:B7X,B7H4,B7S1,B7-H4,B7h.5,VCTN1,PRO1291
基因ID:79679
Chromosome:
(GRCh37)
1 Start: 117686209 End: 117753582 Strand: 
信号通路:  
VTCN1 基因突变与药物

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